Description

Product Description

Decarboxy carnosine HCL, CAS No 57022-38-5, also known as Decarboxy carnosine hydrochloride is a derivative of carnosine. It's a peptide that occurs naturally in the body and helps maintain the health of skin and body. Decarboxy carnosine HCL(CAS No 57022-38-5) is used in skincare products to help with anti-oxidation,anti-aging, and anti-glycation

Decarboxy carnosine HCL (CAS No 57022-38-5) is a stable form of carnosine that is not easily broken down by enzymes. It's non-irritant and non-toxic , making it suitable for sensitive skin.

Basic information

Product Name	Decarboxy carnosine HCL;Decarboxy carnosine hydrochloride;Carcinine dihydrochloride; Carcinine (2HCl)
Chemical Name	3-Amino-N-(2-(1H-imidazol-4-yl)ethyl)propanamide dihydrochlorideDecarboxy Carnosine Hydrochloride
INCI Name	Decarboxy Carnosine HCL
CAS NO.	57022-38-5
MF	C8H16Cl2N4O
MW	255.14
Function	Anti-oxidant

Application

Anti-oxidation

Decarboxy carnosine HCL (CAS No 57022-38-5) acts as an antioxidant to help protect skin from environmental stressors.

Anti-glycation

Decarboxy carnosine HCL(CAS No 57022-38-5) inhibits glycation, which is a process that impairs skin's collagen and elastin.

Other benefits

Decarboxy carnosine HCL can also help maintain skin elasticity, reduce hyperpigmentation, and act as a sun protective agent.

Comparison Table: Decarboxy Carnosine HCl vs. L-Carnosine
Feature / Metric	Decarboxy Carnosine HCl	Standard L-Carnosine
Enzymatic Stability	Highly Resistant (Not degraded by carnosinase)	Low (Rapidly degraded by carnosinase)
Bioavailability in Skin	Prolonged action, extended half-life	Short-lived efficacy
Anti-Glycation Power	⭐⭐⭐⭐⭐ (Prevents cross-linking of collagen)	⭐⭐⭐ (Basic protection)
Formulation Stability	Excellent (No discoloration over time)	Prone to yellowing in certain pH levels

Mechanism of Action: How It Reverses Skin Aging

Decarboxy Carnosine HCl operates through a comprehensive multi-target pathway to protect skin structure:

Scavenging ROS (Antioxidant): Instantly neutralizes reactive oxygen species caused by UV rays and pollution.

Sacrificial Anti-Glycation: It acts as a "decoy" by reacting with reducing sugars before they can bind to the skin's native collagen and elastin.

Preventing AGEs Formation: By blocking the Maillard reaction in the skin, it stops the formation of Advanced Glycation End-products (AGEs), keeping the skin supple and preventing yellowing/sallowness.

Formulation recommendations

Recommended dosage of Decarboxy carnosine HCL in cosmetics

0.1-1.0%

Solubility: 100% Water-soluble.

Processing Method: Add to the water phase at temperatures below 40°C during the final cooling stage of formulation. Compatible with a wide range of standard cosmetic ingredients.

Compatibility suggestion of Decarboxy carnosine HCL

Decarboxy carnosine HCL is easily soluble in water and avoid compatibility with ingredients with Cu2+ or Fe2+.

The aqueous solution of Decarboxy carnosine HCL has a high electrical conductivity, and ionic resistant thickeners are more recommended in preparation.

Precautions

It is recommended that the temperature is lower than 45 °C during the preparation process, and Decarboxy carnosine HCL(CAS No 57022-38-5) should be added in the final stage of the formulation system.

Storage

Stored in cool, dry place, room temperature.

Shelf life

24 months from manufacturing date.

Packing and delivery

Packing

Regular packing of Decarboxy carnosine HCL(CAS No 57022-38-5) is carton or drum with inner packing of two layers of LDPE bags, one layer of Foil bag.

Package can be customized from gram to kg according to your demand.

500g/bag or bottle, 1kg/carton, 10kg/carton, 25kg/drum or customized

Delivery

Common shipment term is by air, by sea, or by express.

Sample and products of Decarboxy carnosine HCL(CAS No 57022-38-5) in small quantity can be delivered by DHL, Fedex,UPS..

Why choose us?

Strict Quality Control

Our quality team including QC and QA members have rich experience in this field. To ensure the quality of the products, we have regular training plan for all the members

Stable Supply

We are both manufacturer and trader, we can source products for you. And guarantee the stable supply.

Fast delivery

For products in stock, we can make prompt delivery as soon as receiving your payment.For synthesis chemicals, we will offer the lead time when making the quotation.

Fast response and good service

Our professional sales team will response you asap within 24 hours.

Company Profile

Shanghai Joy Biotech Ltd. is a professional supplier of Cosmetic ingredients like Decarboxy carnosine HCL, pharmaceutical raw materials, Intermediates, Dietary supplements etc. Our team consists of post-doctor, doctors, masters, Bachelors in the field of chemistry, pharmaceuticals, Biology, Synthetic Biology.

Joy Biotech is your reliable partner in sourcing active ingredients for cosmetics, pharmaceuticals, and Dietary supplements.