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Your Professional Liraglutide Intermediates Supplier

 

Our goal is to become your true partner in the field of cosmetic ingredients in China. Joy BIotech is a professional supplier and manufacturer of cosmetic ingredients,pharmaceutical raw materials, Intermediates, APIs, Dietary supplements, ,etc. Our service covers export & Import, custom synthesis, CMO/CDMO of chemical and synthesis biology products. The factory has accumulated rich manufacturing experience. Our company is committed to applying advanced manufacturing technology and strict quality control standards to every product. The price is competitive and the product is quality-assured, which is a good choice for your long-term cooperation.

 

 

 

 

 

Why Choose Us
 

Quality Control
QC team members are all qualified and receive regular training. A professional QA team ensures quality products and a sound documentation system is in place to support audits.

 

Our Team
Joy Biotech team members include postdocs, doctors, masters, bachelors in the fields of synthetic biopharmaceuticals, chemistry, biology.

 

Our Services
We not only provide quality products, but also the best pre-sales and after-sales services. Our goal is to build a long-term relationship with every customer. If you have questions or problems, please feel free to contact us by email, phone, WhatsApp... We will respond to you as soon as possible within 24 hours.

 

Fast Delivery
For products in stock, we can deliver immediately after receiving your payment. For synthetic chemicals, we will provide delivery time when quoting.

 

Liraglutide

 

Benefits of Liraglutide Intermediates

Other clinical benefits in the liraglutide-treated subjects included improvement in insulin sensitivity and a reduction in CVD risk factors. In addition, 75% of individuals treated with liraglutide achieved normal fasting glucose compared with 19% on placebo.

 

 

Application of Liraglutide Intermediates

Liraglutide injection is used with diet and exercise to lower blood sugar in people with type 2 diabetes. It is also used to reduce the risk of life-threatening events, including heart attack and stroke, in adults with type 2 diabetes and established heart or blood vessel disease.

Boc-His(Trt)-Ala-Glu(OtBu)-Gly-OH

 

Specification of Liraglutide Intermediates

 

 

Product Name

Liraglutide Intermediates

MF

C172H265N43O51

MW

3751.202

Appearance

White to off-white powder

Solubility

Slightly soluble in DMSO and water

Remarks

Not directly for patients.

 

Fmoc-Thr(tBu)-Phe-OH For Liraglutide

 

Production Process of Liraglutide Intermediates

The synthetic methods of the i.e. Arg34-GLP-1 of Liraglutide intermediate polypeptide a kind of, include the following steps: to optimize Liraglutide intermediate gene, and construct its recombinant expression carrier；E. coli bl21 is converted, ferments and induces its expressing fusion protein；It is cleaned by sonicated cells, affinity purification, digestion, affinity column excessively later to obtain the higher Liraglutide intermediate of purity.Preparation cumbersome in chemical synthesis, purification step and excessive impurity, the generation of pollutant and longer production cycle are avoided using gene recombination method.Compared with the method for front, production process is simplified, reduces the generation of production cost and pollutant, more conducively large-scale production.

 

Precautions for Use Liraglutide Intermediates

 
 

Your risk of getting low blood sugar may be higher if you use liraglutide with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Stop using liraglutide and get medical help right away if you have any symptoms of a serious allergic reaction.

 
 

Kidney problems (kidney failure). In people who have kidney problems, diarrhea, nausea, and vomiting may cause a loss of fluids (dehydration) which may cause kidney problems to get worse. Gallbladder problems including gall stones have happened in some people who take liraglutide. Tell your healthcare provider right away if you get symptoms of gallbladder problems.

 
 

Food or liquid getting into the lungs during surgery or other procedures that use anesthesia or deep sleepiness (deep sedation). liraglutide may increase the chance of food getting into your lungs during surgery or other procedures. Tell all your healthcare providers that you are taking liraglutide before you are scheduled to have surgery or other procedures.

 

 

Packing and Delivery of Liraglutide Intermediates

 

 

Packing

10g/bottle; 1kg/bottle or carton; 25kg/drum; Or customize packing size from gram to kg.

Delivery

Deliver by air,by sea,or by express like DHL, Fedex, TNT,etc.

 

FAQ

 

Q: What is the precursor of liraglutide?

A: The precursor of liraglutide is a K34R mutant of GLP-1 (GLP-1R34) and was produced previously by either yeast protein expression system or peptide solid phase synthesis.

Q: Is Ozempic a liraglutide?

A: Ozempic contains the active ingredient semaglutide. Victoza contains the active ingredient liraglutide. Semaglutide and liraglutide belong to the same drug class, called glucagon-like peptide-1 (GLP-1) agonists.

Q: What is the difference between Saxenda and liraglutide?

A: Saxenda and Victoza are brand-name injection pens that contain the same active drug, liraglutide. Saxenda is used for weight management. Victoza is used to treat type 2 diabetes and to lower the risk of heart problems.

Q: What does liraglutide mimic?

A: The class of drugs liraglutide and semaglutide belong to are known as GLP-1 mimetics, meaning they mimic the natural hormone GLP-1. This hormone is released from your small intestines in response to food and acts in several ways to improve the way your body handles glucose (sugar).

Q: How do you increase liraglutide?

A: Patients increase the dose by 0.6 mg each week until the full maintenance dose of 3 mg is reached. Patients who start with a sample pen will need a prescription to complete dosage.

Q: Can I switch from liraglutide to semaglutide?

A: Switching from once-daily liraglutide to once-weekly semaglutide 0.5 mg significantly improved glycemic control and body weight compared with switching to once-weekly dulaglutide 0.75 mg.

Q: Is metformin a liraglutide?

A: Metformin and Victoza (liraglutide) are used for treating type 2 diabetes. Metformin is also used to treat polycystic ovaries and weight gain due to medications used for treating psychoses. Metformin is an oral medication and Victoza is administered by injection under the skin (subcutaneously).

Q: How long can you use liraglutide?

A: Patients who are unable to tolerate the 3-mg dose should stop treatment, as should patients who do not lose 4% of their baseline body weight after four months. If patients achieve clinically significant weight loss after one year, liraglutide may be continued to maintain weight loss.

We're well-known as one of the leading liraglutide intermediates manufacturers and suppliers in China. If you're going to buy high quality liraglutide intermediates, welcome to get quotation from our factory. For price consultation, contact us.

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