Our goal is to be your true partner in the sacubitril intermediate in China.Joy biotech is a professional supplier and manufacturer of cosmetic ingredients,pharmaceutical raw materials, intermediates, apis, dietary supplements, ,etc. Our service covers export & import, custom synthesis, cmo/cdmo of chemical and synthesis biology products. The factory has accumulated rich manufacturing experience. Our company is committed to applying advanced manufacturing technology and strict quality control standards to every product. The price is competitive and the product is quality-assured, which is a good choice for your long-term cooperation.
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![(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic Acid]()
(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-...Product Name：(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acidCAS NO.：1012341-50-2MF：C23H29NO4MW：383.48read more
![(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic Acid](/uploads/43157/small/-2r-4s-5-biphenyl-4-yl-4-tert-butoxycarbonyl6ca11.jpg?size=380x0)
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Quality Control
QC team members are all qualified and receive regular training. A professional QA team ensures quality products and a sound documentation system is in place to support audits.
Our Team
Joy Biotech team members include postdocs, doctors, masters, bachelors in the fields of synthetic biopharmaceuticals, chemistry, biology.
Our Services
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Fast Delivery
For products in stock, we can deliver immediately after receiving your payment. For synthetic chemicals, we will provide delivery time when quoting.
Advantages of Sacubitril Intermediate
Sacubitril/valsartan treatment exerts beneficial hemodynamic effects, including vasodilatation and blood volume reduction, with increased renal sodium and water excretion. It also has a beneficial effect on cardiac remodeling, improving ventricular preload and afterload.
Specification of Sacubitril Intermediate
|
Product Name |
AHU-377 (Sacubitril) |
|
Purity |
99% |
|
Synonyms |
Ethyl (αR,γS)-γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoate hemicalcium salt;LCZ696(valsartan + sacubitril) impurity 1;(alphar;1'-biphenyl]-4-pentanoic acid 4-ethyl ester calcium salt (2:1);gammas)-gamma-[(3-Carboxy-1-oxopropyl)amino]-alpha-methyl-[1;Sacubitril Hemicalcium salt;(αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic acid 4-ethyl ester calcium salt;Sacubitril Calcium |
|
CAS |
1369773-39-6 |
|
MF |
C48H56CaN2O10 |
|
MW |
861.04364 |
|
Product Categories |
Intermediates;lcz696;LCZ 696;Pharmaceutical Intermediates |
|
Mol File |
1369773-39-6.mol |
Usage metering of Sacubitril Intermediate
![(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic Acid](https://www.joybiotech.com/uploads/43157/-2r-4s-5-biphenyl-4-yl-4-tert-butoxycarbonyl6ca11.jpg "productcate-1-1")
Adults—At first, 1 tablet of 49 milligrams (mg) of sacubitril and 51 mg of valsartan 2 times a day. After 2 to 4 weeks, your doctor May increase your dose as needed and tolerated. However, the dose is usually not more than 1 tablet of entresto® 97/103 mg two times a day.
Children 1 year of age and older and weighing at least 50 kilograms (kg)—Dose is based on body weight and must be determined by your doctor. The starting dose is 1 tablet of entresto® 49/51 mg two times a day. Your doctor will increase your dose every 2 weeks as needed and tolerated. However, the dose is usually not more than 1 tablet of entresto® 97/103 mg two times a day.
Children 1 year of age and older and weighing at least 40 kg to less than 50 kg—Dose is based on body weight and must be determined by your doctor. The starting dose is 1 tablet of entresto® 24/26 mg two times a day. Your doctor will increase your dose every 2 weeks as needed and tolerated. However, the dose is usually not more than 3 tablets of entresto® 24/26 mg two times a day.
Children 1 year of age and older and weighing less than 40 kg—Dose is based on body weight and must be determined by your doctor. The starting dose is 1.6 mg per kg of body weight two times a day. Your doctor will increase your dose every 2 weeks as needed and tolerated. However, the dose is usually not more than 3.1 mg per kg of body weight two times a day.
Children younger than 1 year of age—Use and dose must be determined by your doctor.
Packing and Delivery of Sacubitril Intermediate
|
Packing |
Double layers of pe bags, and one layer of an aluminum foil bag inside, and packed in a drum.50g/bottle, 25kg/drum, or customize from gram to kg. |
|
Delivery |
By air; By sea; By express such as DHL,Fedex,TNT etc. |
FAQ
We're well-known as one of the leading sacubitril intermediate manufacturers and suppliers in China. If you're going to buy high quality sacubitril intermediate, welcome to get quotation from our factory. For price consultation, contact us.
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