Description

Basic Information

Product Name:	Alpha-Glyceryl Phosphoryl Choline
CAS NO:	28319-77-9
MF：	C₈H₂₀NO₆P
MW：	257.22
Capacity:	200MT/year
Main sales markets:	European countries, USA, South Korea, india and other South-East Asian countries
Experience:	Production since 2008
Stock:	50MT

Application

Alpha-GPC (Alpha-Glyceryl Phosphoryl Choline) is a naturally occurring choline compound in the body, also synthesized in laboratories for use in dietary supplements.

It has several important applications, primarily related to cognitive and physical performance.

This compound is believed to enhance brain function by boosting acetylcholine, a key neurotransmitter involved in memory and learning.

While Alpha-GPC is commonly used to support cognitive health-including conditions like Alzheimer's disease, stroke recovery, and memory enhancement-scientific evidence supporting these benefits remains limited.

In certain European countries, Alpha-GPC is classified as a prescription medication, whereas in the U.S., it is only available as an over-the-counter supplement. It should not be confused with similar compounds like choline, lecithin, or phosphatidylcholine, as these have distinct properties.

Specification

50% Powder (Water soluble):

Items	Specifications	Metohd
Appearance	White powder	Visual
Identification	Conforms to The standard	TLC
Heavy metals	<10ppm	Colorimetry
Moisture	<3.0%	K.F.
Assay	≥50%	Potentiometric HCIO4 Titration
Total plate count (cfu/g)	≤1000cfu/g	USP
Yeast & mold	≤100cfu/g	USP
Coliforms	Negative	USP
Salmonella	Negative	USP
Product Description: L-a-Glycerylphosphorylcholine:50.0~52.0% Mannitol:47.0-49.5% Silicon dioxide:0.5~1.0% STORE IN COOL DRY PLACE.

50% Powder:

Items	Specifications	Method
Appearance	White powder	Visual
Identification	Conforms to The standard	TLC
Heavy metals	<10ppm	Colorimetry
Moisture	<3.0%	K.F.
Assay	≥50%	Potentiometric HCIO4 Titration
Total plate count (cfu/g)	≤1000cfu/g	USP
Yeast & mold	≤100cfu/g	USP
Coliforms	Negative	USP
Salmonella	Negative	USP
Product Description: L-a-Glycerylphosphorylcholine:50.0~52.0% Dicalcium Phosphate:43.5~48.5% Magnesium stearate:0.5~1.5% Silicon dioxide:0.5~1.5% Magnesium silicate:0.5~1.5% STORE IN COOL DRY PLACE.

99% Powder:

Items	Specifications
Description	White powder, neutral odor, very highly hygroscopic.
Identification(TLC)	Conforms to the standard
Solubility(H2O,10%w/v)	Clear
Stability	Dry and light protected storage; Stable under normal usage.
Optical rotation [a]²⁵D	-2.4° to-2.95°
pH	5.0~7.0
Chloride(CI)	Not more than 0.02%
Sulfate	Not more than 0.02%
Heavy metals(as Pb)	Not more than 10ppm
Phosphate ion	The color of solution should not stronger than the control solution(5ppm)
Glycidol	Not more than 0.4ppm
Chloroglycerin	Not more than 1.0ppm
Total impurities	Not more than 0.5%
Solvents residue (Ethanol)	Not more than 1.0%
Water content	Not more than 2.0%
Single impurity (β -GPC by³¹P NMR) (Others by HPLC)	Not more than 0.1%
Purity (HPLC)	Not less than 99.7%

85% Liquid:

Characteristics	Colorless, clear, viscous liquid
Identification	TLC: Standard solution and test solution same spot, Rf
Optical rotation [a]25 D	-2.45°to-2.74°
Heavy metals (as Pb)	Not more than 10ppm
Sulfate	Not more than 0.02%
Chloride	Not more than 0.02%
Phosphate ion	Not more than 5ppm
Single impurity (β-GPC by³¹P NMR) (Others by HPLC)	Not more than 0.1%
Epichlorohydrin (GCMS)	Not more than 0.04ppm
Glycidol (GCMS)	Not more than 0.4ppm
Chloroglycerin (GCMS)	Not more than 1.0ppm
Residual solvent (ethanol)	Not more than 100ppm
PH	5.5~6.5
Water determination	14.3~15.6%
Purity (HPLC)	Not less than 99.7%
Related substances (TLC)	Any Other Impurity not more than 0.5%; Total impurities not more than 2.0%

Products List

CAS NO.	Product Name
28319-77-9	Alpha-GPC 50%Powder (Water soluble)
28319-77-9	Alpha-GPC 50% Powder
28319-77-9	Alpha-GPC 99% Powder
28319-77-9	Alpha-GPC 75% Liquid
28319-77-9	Alpha-GPC 85% Liquid
107-73-3	Phosphorylcholine