3-O-Ethyl-L-ascorbic Acid CAS NO 86404-04-8

3-O-Ethyl-L-ascorbic Acid CAS NO 86404-04-8
Details:
INCI Name:3-O-ETHYL ASCORBIC ACID
CAS NO.:86404-04-8
MF:C8H12O6
MW:204.18
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Description
 

Product Specification

 

 

Test items Standards

Appearance

White to off white crystal powder

Melting point

111-115℃

Odour

Slight odour

Clarity and Color

Clear colorless

Residue on ignition

≤0.1%

Loss on drying

≤1.0%

Purity(HPLC)

≥99.0%

 

Stability & Performance Data

 

 

 

A. Thermal & Discoloration Stability Test (90-Day Real-Time Stress Test)
 

product-625-265

 

 

 

B. pH-Dependent Degradation Curve Data
Formulators often struggle with the narrow pH window required for traditional Vitamin C. Our lipophilic and hydrophilic amphiphilic structure ensures unmatched resilience across a broad pH spectrum.
Optimal pH Range: 4.0 – 6.0 (Perfect for skin-barrier-friendly formulations).
Degradation Rate: Less than 1.5% active ingredient degradation observed over 12 months within the optimal pH scope.
Formulation Benefit: Eliminates the need for aggressive pH adjusters or high-cost airless packaging. 

 

C. Transdermal Penetration: Pure Vitamin C vs. 3-O-Ethyl-L-Ascorbic Acid
Stability means nothing if the active cannot penetrate the stratum corneum. Thanks to the precise ethyl modification on the 3rd carbon position, our molecule passes seamlessly through lipid bilayers.
Skin Absorption Rate: 4.3x higher skin absorption and retention rate than standard L-Ascorbic Acid.
In-Vivo Conversion: Once absorbed into the epidermis, it is efficiently metabolized into free L-ascorbic acid by native enzymes, providing an immediate 80%+ conversion yield to trigger cellular collagen synthesis and tyrosinase inhibition.

 

 

Application

 

 

  • 3-O-Ethyl-L-ascorbic acid, also known by its alternative name ethyl ascorbic acid, is a derivative of vitamin C (ascorbic acid).
  • It is water-soluble but exhibits partial oil solubility, enhancing its skin absorption efficiency.
  • Brightening the skin/Reducing hyperpigmentation/Evening out skin tone

 

 

Formulation Compatibility & Interactions Guide (Conversion Driver)

 

 

 

product-627-360

 

 

Company Profile

 

 

Shanghai Joy Biotech Ltd. is a reliable supplier of Cosmetic ingredients like 3-O-ethyl-L-ascorbic acid(CAS NO 86404-04-8), Nutritional supplement, Dietary supplements, Pharmaceutical raw materials, Intermediates etc.

The business scope of Joy Biotech involves in export & Import chemical products, custom synthesis, CMO and CDMO .

The R&D team members are professional in the field of pharmaceuticals, chemistry, synthesis Biology.

product-750-500
product-750-500
product-750-500

How to place your order

 

 

1.Send your order demand by email to us(miley@joybiotech.com).

2.We will send you a PROFORMA INVOICE (PI) and SC for confirmation.

3.Arrange the payment after you confirmed the proforma invoice and SC.

4.The production will be arranged as soon as we received your payment, or arrange the shipment if the product is in stock already.

5.For custom synthesis product order, we will need some time to custom synthesize the chemicals, when the goods are ready, the shipment will be arranged after we receiving the balance payment.

6.We will provide the tracking information to you

7.You will receive your goods. If any problems, please contact us immediately.

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Contact Us

Email:miley@joybiotech.com

Whatsapp:+8615968534750

Wechat:mt20230523

 

 

 

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