Methyl-d3-amine Hydrochloride CAS NO 7436-22-8

 

 

Methyl-d3-amine Hydrochloride (CAS 7436-22-8) is a critical deuterated building block primarily utilized as an intermediate in the synthesis of Deucravacitinib (BMS-986165), a novel, selective TYK2 inhibitor. The incorporation of a stable deuterated methyl group ($\text{CD}_3$) is essential for altering drug metabolism, enhancing metabolic stability, and improving the pharmacokinetic profile of the final active pharmaceutical ingredient (API).

At JoyBiotech, we utilize advanced catalytic deuterated synthesis pathways to guarantee exceptional isotopic purity, strict moisture control, and chemical consistency across all commercial and R&D production batches.

 

 

 

Product Name	Methyl-d3-amine hydrochloride
CAS	7436-22-8
Item	Specification
Appearance	White to Off-White solid powder
Water content	NMT 0.3%
Deuterium Ratio	NLT 99%
Purity	NLT 98%

 

 

 

Because Methyl-d3-amine Hydrochloride is highly hygroscopic, exposure to ambient moisture degrades its physical quality and compromises downstream reaction yields. JoyBiotech implements a rigorous moisture barrier protocol:

 

Atmospheric Protection: All products are packaged and sealed under a dry nitrogen/argon atmosphere to prevent any atmospheric moisture contact.

 

Packaging Materials: Standard packaging uses double-layer anti-static, moisture-barrier LDPE bags, further sealed inside high-density polyethylene (HDPE) drums or composite aluminum foil bags with active desiccant packs.

 

Custom Packaging: Flexible B2B packaging options ranging from 100g, 1kg, 5kg, to 25kg commercial drums are available upon request to prevent repeated opening and exposure during pilot production.

 

 

 

Joy Biotech is a professional and reliable supplier of high-quality pharmaceutical raw materials, including:

 

• APIs (Active Pharmaceutical Ingredients)
• Pharmaceutical Intermediates (including Deucravacitinib Intermediates)
• Dietary Supplements
• Cosmetic Ingredients
• Custom Synthesis & CDMO/CMO Services

 

Our R&D Team:
Comprised of highly qualified experts in Chemical Synthesis, Biology, and Pharmaceuticals, our team includes:

Postdoctoral Researchers

PhD Holders

Master's and Bachelor's Degree Professionals