for Advanced Organic & Pharmaceutical Synthesis
2-Iodobenzoic Acid (CAS No. 88-67-5) is a critical functionalized aromatic building block widely utilized in medicinal chemistry, drug discovery, and fine chemical synthesis. As a versatile ortho-halogenated benzoic acid derivative, it serves as a key intermediate in transition-metal catalyzed cross-coupling reactions (such as Suzuki, Heck, and Sonogashira couplings) and lactone/lactam ring cyclizations.
Furthermore, 2-Iodobenzoic Acid is the primary synthetic precursor for high-valent iodine reagents, including 2-Iodoxybenzoic Acid (IBX) and Dess-Martin Periodinane (DMP), which are indispensable selective oxidizing agents in organic synthesis.
Product Specification
| Item | Specification |
| Appearance | White powder |
| CAS | 88-67-5 |
| MF | C7H5IO2 |
| MW | 248.02 |
| Water content | ≤0.5% |
| Purity by HPLC | ≥99.5% |
|
Melting point |
160-162 °C(lit.) |
| Boiling point | 313.9±25.0 °C(Predicted) |
| Store at | Store in a cool, dry place at room temperature |
| Chemical Scaffold Category | Benzoic Acid Derivatives / Halogenated Aromatic Building Blocks |
| Application |
Core building block for pharmaceutical synthesis, heterocyclic scaffold construction, and oxidation reagents (e.g., IBX preparation) |
Similar Building Blocks & Core Scaffolds
| Scaffold Category | Product Name & CAS No. | Application Highlights |
| Benzoic Acid Series | 2-Bromobenzoic Acid (CAS 88-65-3) | Halogenated intermediate for aryl cross-coupling |
| Benzoic Acid Series | 2-Chlorobenzoic Acid (CAS 118-91-2) | Aromatic building block for active ingredients |
| Oxidizing Agent Precursors | 2-Iodoxybenzoic Acid (IBX) (CAS 61717-82-6) | Hypervalent iodine reagent derived from 2-Iodobenzoic Acid |
| Fused Ring Scaffolds | Pyrazolo[1,5-a]pyrimidine Derivatives | Heterocyclic core scaffolds for medicinal chemistry synthesis |
Key Advantages & Commercial Features
High Chemical Purity: Rigorously quality-checked (≥98.0%) to ensure batch-to-batch consistency and high yield in sensitive catalytic reactions.
Versatile Functional Group Reaction Site: Dual functionality (reactive iodo group and carboxylic acid motif) allows rapid assembly of complex pharmaceutical scaffolds and fused heterocyclic systems.
Reliable Commercial Scale: Available from gram-level R&D quantities to commercial multi-kilogram production lots.
Complete Documentation Support: Full Analytical Data Support including Certificate of Analysis (COA), HPLC/NMR spectra, and Safety Data Sheets (SDS) provided with every shipment.
Strict Quality Assurance: Every lot is validated via HPLC and NMR testing.
Global Logistics & Express Delivery: Safe and compliant transport of specialty chemical intermediates worldwide.
Custom Packaging & Bulk Supply: Tailored packaging options from 100g to bulk commercial drums.
Manufacturing Site

Delivery
After receiving the order and payment, we will arrange the shipment as soon as possible.
Shipping terms(e.g.,by air, sea, or express)will be included in the quotation and depend on your requirements.
Samples and products in small quantities are usually shipped via DHL, FedEx, or UPS.
For more details, please contact us at miley@joybiotech.com.

Nice Package
Packaging size can range from 1 gram to 1 kilogram per bottle or bag, and we offer customized sizes based on your requirements and chemical properties of the product.
We prioritize nice packaging to ensure products are well-protected and arrive in perfect condition.

Why choose Joy Biotech?
Direct factory, Competitive price
We are a manufacturer offering factory-direct pricing
Quality control
We are committed to delivering high-quality products, backed by our well-trained QC and QA teams, ensuring quality consistency.
Fast delivery
For products in stock, we arrange immediate shipment upon receiving your payment.
For synthetic chemicals, we specify the lead time when quoting.
Process
Step 1 Send your demand to us (miley@joybiotech.com)
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Step 2 Our professional team will contact you within 24 hours
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Step 3 After Order confirmation, sign the contract and customer pay the deposit.
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Step 4 Joy Biotech begins production if no stock
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Step 5 Joy Biotech sends the COA, and related test data,such as HPLC,GC for customer's approval
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Step 6 Customer pay the balance payment
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Step 7 Product delivery
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Step 8 After-sales service

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