Product Introduction & Overview
10-Hydroxydecanoic Acid (CAS 14113-05-4), also widely recognized as Royal Jelly Acid, is a naturally occurring fatty acid extracted and purified from royal jelly. As a highly specialized bio-active compound, it serves as an exceptional Natural Sebum Regulator and potent anti-acne agent in premium dermatological and cosmetic formulations.
Unlike aggressive synthetic treatments that disrupt the skin barrier, 10-Hydroxydecanoic Acid delivers a multi- targeted approach to restore lipid balance, suppress pathogenic bacteria, and visibly reduce inflammatory acne lesions, making it an indispensable asset for clean-beauty clinical skincare.
Product Specification
| Test items | Standards |
| Appearance |
White to off-white powder
|
|
IR
|
Should be consistent with that of the
reference product
|
|
HPLC
|
The retention time of the main peak of the
test solution should be the same as that of
the control solution
|
|
Melting Point
|
62-66℃
|
|
LOD
|
≤1.0%
|
|
Ignition residue
|
≤0.10%
|
|
Purity
|
98% |
Bio-Based Manufacturing & Extraction Process
Our 10-Hydroxydecanoic Acid is manufactured under strict GMP-compliant conditions, ensuring a sustainable, traceable, and ultra-pure final product suitable for international regulatory compliance.
1.Premium Royal Jelly Sourcing: Harvested from sustainable, ecologically protected apiaries under controlled climatic conditions.
2.Supercritical CO2 & Bio-Enzymatic Extraction: Utilizing advanced, green extraction technology to isolate fatty acid fractions without toxic chemical solvents, preserving molecular integrity.
3.Fractional Crystallization: Sophisticated separation processes to concentrate 10-hydroxydecanoic acid from other lipid matrix elements.
4.High-Vacuum Molecular Distillation: Purifies the compound to an industry-leading standard (≥95% / ≥98% active assays), removing all traces of allergens, heavy metals, and honey impurities.
Scientific Anti-Acne (Anti-Comedogenic) Mechanism
Acne vulgaris is driven by a triad of hyperseborrhea, follicular hyperkeratinization, and Cutibacterium acnes proliferation. 10-Hydroxydecanoic Acid targets these pathophysiological pathways simultaneously:
A. 5-α Reductase Inhibition (The Root Cause of Sebum Overproduction)
Sebum synthesis is triggered when Dihydrotestosterone (DHT) binds to sebocyte receptors, a process catalyzed by the 5-alpha reductase enzyme. 10-Hydroxydecanoic Acid structurally interferes with 5-α reductase activity, downregulating sebum synthesis at the cellular level and preventing the greasy microenvironment that promotes acne formatting.
B. Broad-Spectrum Antimicrobial & Anti-Biofilm Activity
It exhibits robust minimum inhibitory concentrations (MIC) against Cutibacterium acnes, Staphylococcus aureus, and Malassezia furfur. It disrupts the bacterial cell membrane and breaks down protective biofilms, suppressing follicular micro-inflammation.
C. Interleukin-α (IL-1α) Suppression
By modulating inflammatory cytokines (specifically inhibiting IL-1α and TNF-α synthesis), it reduces the swelling, erythema, and post-inflammatory hyperpigmentation (PIH) typically associated with acneic lesions.
Our Advantages
Exceptional Service:
We provide not only qualified products but also superior pre-sales and post-sales support, committed to building lasting customer relationships. Contact us anytime via email, phone, or WhatsApp – we guarantee a response within 24 hours.
Flexible Ordering:
Specifically tailored for start-ups and R&D institutions, we offer gram-scale quantities with no minimum order requirements
Fast Delivery
For products in stock, we can deliver immediately after receiving your payment. For synthetic chemicals, we will provide delivery time when quoting.
Manufacturing Site
Company Profile
Shanghai Joy Biotech Ltd. is a professional supplier of dietary supplements (such as L-Histidine), pharmaceutical raw materials, cosmetic ingredients, and related products. Our team comprises doctors, master's degree holders, and bachelor's degree holders specializing in pharmaceuticals, chemistry, and biology.
We provide professional services in export and import of chemical products, as well as CMO/CDMO (Contract Manufacturing Organization/Contract Development and Manufacturing Organization) solutions.
Our Certificates
Our certificates are complete and trustworthy
